Author: vivian

Introduction Membrane proteins are essential for cellular processes like signaling, transport, and energy conversion. However, their hydrophobic nature and interactions with lipid bilayers make them difficult to study. Traditional methods, such as detergent solubilization, often distort their structure and function, limiting accurate analysis. Nanodiscs provide a solution by offering a stable, native-like environment that preserves membrane protein integrity. These lipid bilayers, stabilized by scaffold proteins, allow for controlled, physiologically relevant studies. By enabling high-resolution structural analysis, functional assays, and drug discovery, nanodiscs are transforming membrane protein research and advancing our understanding of their roles in health and disease. Membrane Proteins…